Incapacitation of a pilot due to the effects of a medical condition or a physiological impairment represents a serious potential threat to flight safety. The purpose of this research project was to investigate the prevalence, type, nature and significance of in-flight medical conditions and incapacitation events occurring in civil aviation. A search of the Australian Transport Safety Bureau's accident and incident database was conducted for medical conditions and incapacitation events between 1 January 1975 and 31 March 2006. There were 98 occurrences in which the pilot of the aircraft was…